Mucolipin-2 also known as TRPML2 (transient receptor potential cation channel, mucolipin subfamily, member 2) is a protein that in humans is encoded by the MCOLN2 gene. It is a member of the small family of the TRPML channels, a subgroup of the large protein family of TRP ion channels.
TRPML2 is associated with the Arf6-regulated trafficking pathway and is involved in the intracellular transport of membranes and membrane proteins.
See also
- transient receptor potential cation channel, mucolipin subfamily, member 1 (MCOLN1)
- transient receptor potential cation channel, mucolipin subfamily, member 3 (MCOLN3)
- TRPML
External links
- MCOLN2+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
References
Clapham DE, Julius D, Montell C, Schultz G (December 2005). "International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels". Pharmacol. Rev. 57 (4): 427–50. doi:10.1124/pr.57.4.6. PMID 16382100. S2CID 17936350. /wiki/Doi_(identifier) ↩
Karacsonyi C, Miguel AS, Puertollano R (October 2007). "Mucolipin-2 localizes to the Arf6-associated pathway and regulates recycling of GPI-APs". Traffic. 8 (10): 1404–14. doi:10.1111/j.1600-0854.2007.00619.x. PMID 17662026. S2CID 25624298. https://zenodo.org/record/1000701 ↩